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Long-Term Treatment with Bortezomib Induces Specific Methylation Changes in Differentiated Neuronal Cells
SIMPLE SUMMARY: We exposed LUHMES cells, differentiated into mature neurons, to bortezomib (BTZ) in two treatment cycles and analyzed the methylomes of these cells after each cycle, controlling the analysis for the methylation changes potentially induced by the long-term culture. Our results show th...
Autores principales: | Łuczkowska, Karolina, Taryma-Leśniak, Olga, Bińkowski, Jan, Sokołowska, Katarzyna E., Strapagiel, Dominik, Jarczak, Justyna, Paczkowska, Edyta, Machaliński, Bogusław, Wojdacz, Tomasz K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319119/ https://www.ncbi.nlm.nih.gov/pubmed/35884461 http://dx.doi.org/10.3390/cancers14143402 |
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