Phagocytosis of Erythrocytes from Gaucher Patients Induces Phenotypic Modifications in Macrophages, Driving Them toward Gaucher Cells

Gaucher disease (GD) is caused by glucocerebrosidase deficiency leading to the accumulation of sphingolipids in macrophages named “Gaucher’s Cells”. These cells are characterized by deregulated expression of cell surface markers, abnormal secretion of inflammatory cytokines, and iron sequestration....

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Detalles Bibliográficos
Autores principales: Dupuis, Lucie, Chauvet, Margaux, Bourdelier, Emmanuelle, Dussiot, Michaël, Belmatoug, Nadia, Le Van Kim, Caroline, Chêne, Arnaud, Franco, Mélanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319206/
https://www.ncbi.nlm.nih.gov/pubmed/35886988
http://dx.doi.org/10.3390/ijms23147640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319206/
https://www.ncbi.nlm.nih.gov/pubmed/35886988
http://dx.doi.org/10.3390/ijms23147640

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