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Emerging Concepts in Defective Macrophage Phagocytosis in Cystic Fibrosis

Cystic fibrosis (CF) is caused by mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Chronic inflammation and decline in lung function are major reasons for morbidity in CF. Mutant CFTR expressed in phagocytic cells such as macrophages contributes to persistent infecti...

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Detalles Bibliográficos
Autores principales: Jaganathan, Devi, Bruscia, Emanuela M., Kopp, Benjamin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319215/
https://www.ncbi.nlm.nih.gov/pubmed/35887098
http://dx.doi.org/10.3390/ijms23147750