Assessing Drug-Induced Mitochondrial Toxicity in Cardiomyocytes: Implications for Preclinical Cardiac Safety Evaluation

Drug-induced cardiotoxicity not only leads to the attrition of drugs during development, but also contributes to the high morbidity and mortality rates of cardiovascular diseases. Comprehensive testing for proarrhythmic risks of drugs has been applied in preclinical cardiac safety assessment for ove...

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Detalles Bibliográficos
Autores principales: Tang, Xiaoli, Wang, Zengwu, Hu, Shengshou, Zhou, Bingying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319223/
https://www.ncbi.nlm.nih.gov/pubmed/35890211
http://dx.doi.org/10.3390/pharmaceutics14071313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319223/
https://www.ncbi.nlm.nih.gov/pubmed/35890211
http://dx.doi.org/10.3390/pharmaceutics14071313

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