Self-Emulsifying Drug Delivery Systems: An Alternative Approach to Improve Brain Bioavailability of Poorly Water-Soluble Drugs through Intranasal Administration

Efforts in discovering new and effective neurotherapeutics are made daily, although most fail to reach clinical trials. The main reason is their poor bioavailability, related to poor aqueous solubility, limited permeability through biological membranes, and the hepatic first-pass metabolism. Neverth...

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Detalles Bibliográficos
Autores principales: Meirinho, Sara, Rodrigues, Márcio, Santos, Adriana O., Falcão, Amílcar, Alves, Gilberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319231/
https://www.ncbi.nlm.nih.gov/pubmed/35890385
http://dx.doi.org/10.3390/pharmaceutics14071487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319231/
https://www.ncbi.nlm.nih.gov/pubmed/35890385
http://dx.doi.org/10.3390/pharmaceutics14071487

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