Targeting the CD47-SIRPα Innate Immune Checkpoint to Potentiate Antibody Therapy in Cancer by Neutrophils

SIMPLE SUMMARY: Immunotherapy aims to engage various immune cells in the elimination of cancer cells. Neutrophils are the most abundant leukocytes in the circulation and have unique mechanisms by which they can kill cancer cells opsonized by antibodies. However, neutrophil effector functions are lim...

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Detalles Bibliográficos
Autores principales: Behrens, Leonie M., van den Berg, Timo K., van Egmond, Marjolein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319280/
https://www.ncbi.nlm.nih.gov/pubmed/35884427
http://dx.doi.org/10.3390/cancers14143366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319280/
https://www.ncbi.nlm.nih.gov/pubmed/35884427
http://dx.doi.org/10.3390/cancers14143366

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