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The Catalytic Domain of Neuropathy Target Esterase Influences Lipid Droplet Biogenesis and Lipid Metabolism in Human Neuroblastoma Cells

As an endoplasmic reticulum (ER)-anchored phospholipase, neuropathy target esterase (NTE) catalyzes the deacylation of lysophosphatidylcholine (LPC) and phosphatidylcholine (PC). The catalytic domain of NTE (NEST) exhibits comparable activity to NTE and binds to lipid droplets (LD). In the current s...

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Detalles Bibliográficos
Autores principales: He, Lin, Huang, Feifei, Wang, Yu, Wu, Yijun, Xu, Li, Chang, Pingan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319352/
https://www.ncbi.nlm.nih.gov/pubmed/35888761
http://dx.doi.org/10.3390/metabo12070637