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Immunosuppression by Mycophenolate Mofetil Mitigates Intrarenal Angiotensinogen Augmentation in Angiotensin II-Dependent Hypertension

Augmentation of intrarenal angiotensinogen (AGT) leads to further formation of intrarenal angiotensin II (Ang II) and the development of hypertensive kidney injury. Recent studies demonstrated that macrophages and the enhanced production of pro-inflammatory cytokines can be crucial mediators of rena...

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Detalles Bibliográficos
Autores principales: Satou, Ryousuke, Franco, Martha, Dugas, Courtney M., Katsurada, Akemi, Navar, L. Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319385/
https://www.ncbi.nlm.nih.gov/pubmed/35887028
http://dx.doi.org/10.3390/ijms23147680