Biosynthetic Nanobubble-Mediated CRISPR/Cas9 Gene Editing of Cdh2 Inhibits Breast Cancer Metastasis

The epithelial-mesenchymal transition (EMT), a process in which epithelial cells undergo a series of biochemical changes to acquire a mesenchymal phenotype, has been linked to tumor metastasis. Here, we present a novel strategy for knocking out the EMT-related Cdh2 gene, which encodes N-cadherin thr...

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Detalles Bibliográficos
Autores principales: Gao, Ruru, Luo, Qiong, Li, Yang, Song, Liming, Cai, Junnan (Stephen), Xiong, Ying, Yan, Fei, Liu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319454/
https://www.ncbi.nlm.nih.gov/pubmed/35890278
http://dx.doi.org/10.3390/pharmaceutics14071382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319454/
https://www.ncbi.nlm.nih.gov/pubmed/35890278
http://dx.doi.org/10.3390/pharmaceutics14071382

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