Membrane Targeting and GTPase Activity of Rab7 Are Required for Its Ubiquitination by RNF167

Rab7 is a GTPase that controls late endosome and lysosome trafficking. Recent studies have demonstrated that Rab7 is ubiquitinated, a post-translational modification mediated by an enzymatic cascade. To date, only one ubiquitin E3 ligase and one deubiquitinase have been identified in regulating Rab7...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghilarducci, Kim, Cabana, Valérie C., Harake, Ali, Cappadocia, Laurent, Lussier, Marc P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319455/
https://www.ncbi.nlm.nih.gov/pubmed/35887194
http://dx.doi.org/10.3390/ijms23147847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319455/
https://www.ncbi.nlm.nih.gov/pubmed/35887194
http://dx.doi.org/10.3390/ijms23147847

Ejemplares similares