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UHPLC/MS-Based Serum Metabolomics Reveals the Mechanism of Radiation-Induced Thrombocytopenia in Mice

Radiation-induced thrombocytopenia is a common and life-threatening side effect of ionizing radiation (IR) therapy. However, the underlying pathological mechanisms remain unclear. In the present study, irradiation was demonstrated to significantly reduce platelet levels, inhibit megakaryocyte differ...

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Detalles Bibliográficos
Autores principales: Xiong, Ling, Wang, Long, Zhang, Ting, Ye, Xinyuan, Huang, Feihong, Huang, Qianqian, Huang, Xinwu, Wu, Jianming, Zeng, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319504/
https://www.ncbi.nlm.nih.gov/pubmed/35887324
http://dx.doi.org/10.3390/ijms23147978