The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca(2+) Homeostasis by Targeting a Unique Ion Channel

Malaria elimination urgently needs novel antimalarial therapies that transcend resistance, toxicity, and high costs. Our multicentric international collaborative team focuses on developing multistage antimalarials that exhibit novel mechanisms of action. Here, we describe the design, synthesis, and...

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Detalles Bibliográficos
Autores principales: Gupta, Yash, Sharma, Neha, Singh, Snigdha, Romero, Jesus G., Rajendran, Vinoth, Mogire, Reagan M., Kashif, Mohammad, Beach, Jordan, Jeske, Walter, Poonam, Ogutu, Bernhards R., Kanzok, Stefan M., Akala, Hoseah M., Legac, Jennifer, Rosenthal, Philip J., Rademacher, David J., Durvasula, Ravi, Singh, Agam P., Rathi, Brijesh, Kempaiah, Prakasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319510/
https://www.ncbi.nlm.nih.gov/pubmed/35890267
http://dx.doi.org/10.3390/pharmaceutics14071371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319510/
https://www.ncbi.nlm.nih.gov/pubmed/35890267
http://dx.doi.org/10.3390/pharmaceutics14071371

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