The Protective Effect of Edaravone on TDP-43 Plus Oxidative Stress-Induced Neurotoxicity in Neuronal Cells: Analysis of Its Neuroprotective Mechanisms Using RNA Sequencing

Edaravone is a free-radical scavenger drug that was recently approved for the treatment of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease. A pathological hallmark of ALS is the accumulation of ubiquitinated or phosphorylated aggregates of the 43-kDa transactive response DNA binding...

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Detalles Bibliográficos
Autores principales: Soejima-Kusunoki, Aki, Okada, Kinya, Saito, Ryuta, Watabe, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319738/
https://www.ncbi.nlm.nih.gov/pubmed/35890141
http://dx.doi.org/10.3390/ph15070842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319738/
https://www.ncbi.nlm.nih.gov/pubmed/35890141
http://dx.doi.org/10.3390/ph15070842

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