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Protective Human Anti-Poxvirus Monoclonal Antibodies Are Generated from Rare Memory B Cells Isolated by Multicolor Antigen Tetramers

Smallpox, an epidemic disease caused by Orthopoxvirus variola, was eradicated worldwide through immunization. The immunization against smallpox was discontinued in 1980. However, incidences of monkeypox virus infection in humans have occurred sporadically, and there is also great fear that engineere...

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Detalles Bibliográficos
Autores principales: Gu, Xiuling, Zhang, Yufan, Jiang, Wei, Wang, Dongfang, Lu, Jiao, Gu, Guanglei, Qin, Chengfeng, Fang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319751/
https://www.ncbi.nlm.nih.gov/pubmed/35891248
http://dx.doi.org/10.3390/vaccines10071084