Synthesis, In Vitro Antiproliferative Activity, and In Silico Evaluation of Novel Oxiranyl-Quinoxaline Derivatives

The quinoxaline core is a promising scaffold in medicinal chemistry. Multiple quinoxaline derivatives, such as the topoisomerase IIβ inhibitor XK-469 and the tissue transglutaminase 2 inhibitor GK-13, have been evaluated for their antiproliferative activity. Previous work reported that quinoxaline d...

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Detalles Bibliográficos
Autores principales: Montero, Vincent, Montana, Marc, Khoumeri, Omar, Correard, Florian, Estève, Marie-Anne, Vanelle, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319868/
https://www.ncbi.nlm.nih.gov/pubmed/35890083
http://dx.doi.org/10.3390/ph15070781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319868/
https://www.ncbi.nlm.nih.gov/pubmed/35890083
http://dx.doi.org/10.3390/ph15070781

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