Age Worsens the Cognitive Phenotype in Mice Carrying the Thr92Ala-DIO2 Polymorphism

The Thr92Ala-Dio2 polymorphism has been associated with reduced cognition in 2-month-old male mice and increased risk for cognitive impairment and Alzheimer’s disease in African Americans. This has been attributed to reduced thyroid hormone (TH) signaling and endoplasmic reticulum (ER) stress in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Lorena, Fernanda B., Sato, Juliana M., Coviello, Beatriz Martin, Arnold, Alexandre J. T., Batistuzzo, Alice, Yamanouchi, Laís M., Dias Junior, Eduardo, do Nascimento, Bruna P. P., Fonseca, Tatiana de L., Bianco, Antonio C., Ribeiro, Miriam O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319877/
https://www.ncbi.nlm.nih.gov/pubmed/35888752
http://dx.doi.org/10.3390/metabo12070629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319877/
https://www.ncbi.nlm.nih.gov/pubmed/35888752
http://dx.doi.org/10.3390/metabo12070629

Ejemplares similares