Crucial Role of Oncogenic KRAS Mutations in Apoptosis and Autophagy Regulation: Therapeutic Implications

KRAS, one of the RAS protein family members, plays an important role in autophagy and apoptosis, through the regulation of several downstream effectors. In cancer cells, KRAS mutations confer the constitutive activation of this oncogene, stimulating cell proliferation, inducing autophagy, suppressin...

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Detalles Bibliográficos
Autores principales: Ferreira, Anabela, Pereira, Flávia, Reis, Celso, Oliveira, Maria José, Sousa, Maria João, Preto, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319879/
https://www.ncbi.nlm.nih.gov/pubmed/35883626
http://dx.doi.org/10.3390/cells11142183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319879/
https://www.ncbi.nlm.nih.gov/pubmed/35883626
http://dx.doi.org/10.3390/cells11142183

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