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A Regulatory Axis between Epithelial Splicing Regulatory Proteins and Estrogen Receptor α Modulates the Alternative Transcriptome of Luminal Breast Cancer

Epithelial splicing regulatory proteins 1 and 2 (ESRP1/2) control the splicing pattern during epithelial to mesenchymal transition (EMT) in a physiological context and in cancer, including breast cancer (BC). Here, we report that ESRP1, but not ESRP2, is overexpressed in luminal BCs of patients with...

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Detalles Bibliográficos
Autores principales: Elhasnaoui, Jamal, Ferrero, Giulio, Miano, Valentina, Franchitti, Lorenzo, Tarulli, Isabella, Coscujuela Tarrero, Lucia, Cutrupi, Santina, De Bortoli, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319905/
https://www.ncbi.nlm.nih.gov/pubmed/35887187
http://dx.doi.org/10.3390/ijms23147835