Repositioning Linagliptin for the Mitigation of Cadmium-Induced Testicular Dysfunction in Rats: Targeting HMGB1/TLR4/NLRP3 Axis and Autophagy

Cadmium, a ubiquitous environmental toxicant, disrupts testicular function and fertility. The dipeptidyl peptidase-4 inhibitor linagliptin has shown pronounced anti-inflammatory and anti-apoptotic features; however, its effects against cadmium-evoked testicular impairment have not been examined. Her...

Descripción completa

Detalles Bibliográficos
Autores principales: Arab, Hany H., Elhemiely, Alzahraa A., El-Sheikh, Azza A. K., Khabbaz, Hana J. Al, Arafa, El-Shaimaa A., Ashour, Ahmed M., Kabel, Ahmed M., Eid, Ahmed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319949/
https://www.ncbi.nlm.nih.gov/pubmed/35890148
http://dx.doi.org/10.3390/ph15070852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319949/
https://www.ncbi.nlm.nih.gov/pubmed/35890148
http://dx.doi.org/10.3390/ph15070852

Ejemplares similares