Novel Design of RNA Aptamers as Cancer Inhibitors and Diagnosis Targeting the Tyrosine Kinase Domain of the NT-3 Growth Factor Receptor Using a Computational Sequence-Based Approach

Aptamers, the nucleic acid analogs of antibodies, bind to their target molecules with remarkable specificity and sensitivity, making them promising diagnostic and therapeutic tools. The systematic evolution of ligands by exponential enrichment (SELEX) is time-consuming and expensive. However, regard...

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Detalles Bibliográficos
Autores principales: Muhammad, Ashraf M., Zari, Ali, Alsubhi, Nouf H., Al-Zahrani, Maryam H., Alghamdi, Rana Abdullah, Labib, Mai M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320020/
https://www.ncbi.nlm.nih.gov/pubmed/35889390
http://dx.doi.org/10.3390/molecules27144518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320020/
https://www.ncbi.nlm.nih.gov/pubmed/35889390
http://dx.doi.org/10.3390/molecules27144518

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