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N(6)-Methyladenosine RNA-Binding Protein YTHDF1 in Gastrointestinal Cancers: Function, Molecular Mechanism and Clinical Implication

SIMPLE SUMMARY: N(6)-methyladenosine (m(6)A) is the most abundant internal modification in eukaryotic mRNA and plays a crucial role in the occurrence and development of diseases. YTHDF1 is the most powerful and abundant m(6)A-encoded RNA reader. In this review, we summarize the evidence of the invol...

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Detalles Bibliográficos
Autores principales: Chen, Danyu, Cheung, Henley, Lau, Harry Cheuk-Hay, Yu, Jun, Wong, Chi Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320224/
https://www.ncbi.nlm.nih.gov/pubmed/35884552
http://dx.doi.org/10.3390/cancers14143489