Maleimide-Functionalized Liposomes: Prolonged Retention and Enhanced Efficacy of Doxorubicin in Breast Cancer with Low Systemic Toxicity

Cell surface thiols can be targeted by thiol-reactive groups of various materials such as peptides, nanoparticles, and polymers. Here, we used the maleimide group, which can rapidly and covalently conjugate with thiol groups, to prepare surface-modified liposomes (M-Lip) that prolong retention of do...

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Detalles Bibliográficos
Autores principales: Tang, Chuane, Yin, Dan, Liu, Tianya, Gou, Rui, Fu, Jiao, Tang, Qi, Wang, Yao, Zou, Liang, Li, Hanmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320254/
https://www.ncbi.nlm.nih.gov/pubmed/35889500
http://dx.doi.org/10.3390/molecules27144632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320254/
https://www.ncbi.nlm.nih.gov/pubmed/35889500
http://dx.doi.org/10.3390/molecules27144632

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