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A kNGR Peptide-Tethered Lipid–Polymer Hybrid Nanocarrier-Based Synergistic Approach for Effective Tumor Therapy: Development, Characterization, Ex-Vivo, and In-Vivo Assessment

The present study aims to design, develop and characterize kNGR (Asn-Gly-Arg) peptide-conjugated lipid–polymer-based nanoparticles for the target-specific delivery of anticancer bioactive(s), i.e., Paclitaxel (PTX). The kNGR-PEG-DSPE conjugate was synthesized and characterized by using spectral anal...

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Detalles Bibliográficos
Autores principales: Gupta, Madhu, Sharma, Vikas, Sharma, Kalicharan, Kumar, Anoop, Sharma, Ajay, Kazmi, Imran, Al-Abbasi, Fahad A., Alzarea, Sami I., Afzal, Obaid, Altamimi, Abdulmalik Saleh Alfawaz, Singh, Sachin Kumar, Gupta, Gaurav, Paudel, Keshav Raj, Hansbro, Philip M., Dua, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320317/
https://www.ncbi.nlm.nih.gov/pubmed/35890297
http://dx.doi.org/10.3390/pharmaceutics14071401