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A kNGR Peptide-Tethered Lipid–Polymer Hybrid Nanocarrier-Based Synergistic Approach for Effective Tumor Therapy: Development, Characterization, Ex-Vivo, and In-Vivo Assessment
The present study aims to design, develop and characterize kNGR (Asn-Gly-Arg) peptide-conjugated lipid–polymer-based nanoparticles for the target-specific delivery of anticancer bioactive(s), i.e., Paclitaxel (PTX). The kNGR-PEG-DSPE conjugate was synthesized and characterized by using spectral anal...
Autores principales: | Gupta, Madhu, Sharma, Vikas, Sharma, Kalicharan, Kumar, Anoop, Sharma, Ajay, Kazmi, Imran, Al-Abbasi, Fahad A., Alzarea, Sami I., Afzal, Obaid, Altamimi, Abdulmalik Saleh Alfawaz, Singh, Sachin Kumar, Gupta, Gaurav, Paudel, Keshav Raj, Hansbro, Philip M., Dua, Kamal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320317/ https://www.ncbi.nlm.nih.gov/pubmed/35890297 http://dx.doi.org/10.3390/pharmaceutics14071401 |
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