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Allostery Inhibition of BACE1 by Psychotic and Meroterpenoid Drugs in Alzheimer’s Disease Therapy

In over a century since its discovery, Alzheimer’s disease (AD) has continued to be a global health concern due to its incurable nature and overwhelming increase among older people. In this paper, we give an overview of the efforts of researchers towards identifying potent BACE1 exosite-binding anti...

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Detalles Bibliográficos
Autores principales: Ugbaja, Samuel C., Lawal, Isiaka A., Abubakar, Bahijjahtu H., Mushebenge, Aganze G., Lawal, Monsurat M., Kumalo, Hezekiel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320338/
https://www.ncbi.nlm.nih.gov/pubmed/35889246
http://dx.doi.org/10.3390/molecules27144372