Preclinical Evaluation of a New Format of (68)Ga- and (111)In-Labeled Affibody Molecule Z(IGF-1R:4551) for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT

The Insulin-like growth factor-1 receptor (IGF-1R) is a molecular target for several monoclonal antibodies undergoing clinical evaluation as anticancer therapeutics. The non-invasive detection of IGF-1R expression in tumors might enable stratification of patients for specific treatment and improve t...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yongsheng, Yu, Shengze, Xu, Tianqi, Bodenko, Vitalina, Orlova, Anna, Oroujeni, Maryam, Rinne, Sara S., Tolmachev, Vladimir, Vorobyeva, Anzhelika, Gräslund, Torbjörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320461/
https://www.ncbi.nlm.nih.gov/pubmed/35890370
http://dx.doi.org/10.3390/pharmaceutics14071475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320461/
https://www.ncbi.nlm.nih.gov/pubmed/35890370
http://dx.doi.org/10.3390/pharmaceutics14071475

Ejemplares similares