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Plasmodium falciparum S-Adenosylmethionine Synthetase Is Essential for Parasite Survival through a Complex Interaction Network with Cytoplasmic and Nuclear Proteins

S-adenosylmethionine synthetase (SAMS) is a key enzyme for the synthesis of the lone methyl donor S-adenosyl methionine (SAM), which is involved in transmethylation reactions and hence required for cellular processes such as DNA, RNA, and histone methylation, but also polyamine biosynthesis and prot...

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Detalles Bibliográficos
Autores principales: Musabyimana, Jean Pierre, Distler, Ute, Sassmannshausen, Juliane, Berks, Christina, Manti, Janice, Bennink, Sandra, Blaschke, Lea, Burda, Paul-Christian, Flammersfeld, Ansgar, Tenzer, Stefan, Ngwa, Che Julius, Pradel, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320499/
https://www.ncbi.nlm.nih.gov/pubmed/35889137
http://dx.doi.org/10.3390/microorganisms10071419