Fabrication and Characterization of Tedizolid Phosphate Nanocrystals for Topical Ocular Application: Improved Solubilization and In Vitro Drug Release

Positively charged NCs of TZP (0.1%, w/v) for ocular use were prepared by the antisolvent precipitation method. TZP is a novel 5-Hydroxymethyl-Oxazolidinone class of antibiotic and is effective against many drug-resistant bacterial infections. Even the phosphate salt of this drug is poorly soluble,...

Descripción completa

Detalles Bibliográficos
Autores principales: Kalam, Mohd Abul, Iqbal, Muzaffar, Alshememry, Abdullah, Alkholief, Musaed, Alshamsan, Aws
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320520/
https://www.ncbi.nlm.nih.gov/pubmed/35890223
http://dx.doi.org/10.3390/pharmaceutics14071328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320520/
https://www.ncbi.nlm.nih.gov/pubmed/35890223
http://dx.doi.org/10.3390/pharmaceutics14071328

Ejemplares similares