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Metformin Treatment Induces Different Response in Pheochromocytoma/Paraganglioma Tumour Cells and in Primary Fibroblasts

SIMPLE SUMMARY: Pheochromocytoma/paragangliomas (PPGLs) are neuroendocrine tumours and are often non-metastatic. However, no effective treatment is available for their metastatic form. Recent studies have shown that metformin exhibits antiproliferative activity in many human cancers, including PPGLs...

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Detalles Bibliográficos
Autores principales: Martinelli, Serena, Amore, Francesca, Mello, Tommaso, Mannelli, Massimo, Maggi, Mario, Rapizzi, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320533/
https://www.ncbi.nlm.nih.gov/pubmed/35884532
http://dx.doi.org/10.3390/cancers14143471