CLL-Derived Extracellular Vesicles Impair T-Cell Activation and Foster T-Cell Exhaustion via Multiple Immunological Checkpoints

Background: Chronic lymphocytic leukemia (CLL) is characterized by the clonal expansion of malignant B-cells and multiple immune defects. This leads, among others, to severe infectious complications and inefficient immune surveillance. T-cell deficiencies in CLL include enhanced immune(-metabolic) e...

Descripción completa

Detalles Bibliográficos
Autores principales: Böttcher, Martin, Böttcher-Loschinski, Romy, Kahlfuss, Sascha, Aigner, Michael, Gießl, Andreas, Mackensen, Andreas, Schlötzer-Schrehardt, Ursula, Tüting, Thomas, Bruns, Heiko, Mougiakakos, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320608/
https://www.ncbi.nlm.nih.gov/pubmed/35883619
http://dx.doi.org/10.3390/cells11142176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320608/
https://www.ncbi.nlm.nih.gov/pubmed/35883619
http://dx.doi.org/10.3390/cells11142176

Ejemplares similares