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CLL-Derived Extracellular Vesicles Impair T-Cell Activation and Foster T-Cell Exhaustion via Multiple Immunological Checkpoints

Background: Chronic lymphocytic leukemia (CLL) is characterized by the clonal expansion of malignant B-cells and multiple immune defects. This leads, among others, to severe infectious complications and inefficient immune surveillance. T-cell deficiencies in CLL include enhanced immune(-metabolic) e...

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Detalles Bibliográficos
Autores principales:	Böttcher, Martin, Böttcher-Loschinski, Romy, Kahlfuss, Sascha, Aigner, Michael, Gießl, Andreas, Mackensen, Andreas, Schlötzer-Schrehardt, Ursula, Tüting, Thomas, Bruns, Heiko, Mougiakakos, Dimitrios
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320608/ https://www.ncbi.nlm.nih.gov/pubmed/35883619 http://dx.doi.org/10.3390/cells11142176

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