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Preparation of Terbinafin-Encapsulated Solid Lipid Nanoparticles Containing Antifungal Carbopol(®) Hydrogel with Improved Efficacy: In Vitro, Ex Vivo and In Vivo Study

The present research was aimed to develop a terbinafin hydrochloride (TH)-encapsulated solid lipid nanoparticles (SLNs) hydrogel for improved antifungal efficacy. TH-loaded SLNs were obtained from glyceryl monostearate (lipid) and Pluronic(®) F68 (surfactant) employing high-pressure homogenization....

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Detalles Bibliográficos
Autores principales: Rarokar, Nilesh R., Menghani, Sunil S., Kerzare, Deweshri R., Khedekar, Pramod B., Bharne, Ashish P., Alamri, Abdulhakeem S., Alsanie, Walaa F., Alhomrani, Majid, Sreeharsha, Nagaraja, Asdaq, Syed Mohammed Basheeruddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320640/
https://www.ncbi.nlm.nih.gov/pubmed/35890289
http://dx.doi.org/10.3390/pharmaceutics14071393