Profile of TREM2-Derived circRNA and mRNA Variants in the Entorhinal Cortex of Alzheimer’s Disease Patients

Genetic variants in TREM2, a microglia-related gene, are well-known risk factors for Alzheimer’s disease (AD). Here, we report that TREM2 originates from circular RNAs (circRNAs), a novel class of non-coding RNAs characterized by a covalent and stable closed-loop structure. First, divergent primers...

Descripción completa

Detalles Bibliográficos
Autores principales: Urdánoz-Casado, Amaya, de Gordoa, Javier Sánchez-Ruiz, Robles, Maitane, Roldan, Miren, Zelaya, María Victoria, Blanco-Luquin, Idoia, Mendioroz, Maite
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320643/
https://www.ncbi.nlm.nih.gov/pubmed/35887031
http://dx.doi.org/10.3390/ijms23147682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320643/
https://www.ncbi.nlm.nih.gov/pubmed/35887031
http://dx.doi.org/10.3390/ijms23147682

Ejemplares similares