Quality Control Dissolution Data Is Biopredictive for a Modified Release Ropinirole Formulation: Virtual Experiment with the Use of Re-Developed and Verified PBPK Model

Physiologically based pharmacokinetic and absorption modeling are being used by industry and regulatory bodies to address various scientifically challenging questions. While there is high confidence in the prediction of exposure for the BCS class I drugs administered as immediate-release formulation...

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Detalles Bibliográficos
Autores principales: Shuklinova, Olha, Dorożyński, Przemysław, Kulinowski, Piotr, Polak, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320685/
https://www.ncbi.nlm.nih.gov/pubmed/35890408
http://dx.doi.org/10.3390/pharmaceutics14071514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320685/
https://www.ncbi.nlm.nih.gov/pubmed/35890408
http://dx.doi.org/10.3390/pharmaceutics14071514

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