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“Endothelial Antibody Factory” at the Blood Brain Barrier: Novel Approach to Therapy of Neurodegenerative Diseases

The failures of anti-β-amyloid immunotherapies suggested that the very low fraction of injected antibodies reaching the brain parenchyma due to the filtering effect of the BBB may be a reason for the lack of therapeutic effect. However, there is no treatment, as yet, for the amyotrophic lateral scle...

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Detalles Bibliográficos
Autores principales: Thinard, Reynald, Farkas, Attila E., Halasa, Marta, Chevalier, Melanie, Brodaczewska, Klaudia, Majewska, Aleksandra, Zdanowski, Robert, Paprocka, Maria, Rossowska, Joanna, Duc, Lam Tri, Greferath, Ruth, Krizbai, Istvan, Van Leuven, Fred, Kieda, Claudine, Nicolau, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320725/
https://www.ncbi.nlm.nih.gov/pubmed/35890313
http://dx.doi.org/10.3390/pharmaceutics14071418