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Effects of Lipid Shape and Interactions on the Conformation, Dynamics, and Curvature of Ultrasound-Responsive Liposomes

We perform coarse-grained molecular dynamics simulations of bilayers composed of various lipids and cholesterol at their different ratios. Simulations show that cholesterol-lipid interactions restrict the lateral dynamics of bilayers but also promote bilayer curvature, indicating that these opposite...

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Detalles Bibliográficos
Autores principales: Lee, Hwankyu, Moon, Hyungwon, Kim, Hyun-Ryoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320727/
https://www.ncbi.nlm.nih.gov/pubmed/35890407
http://dx.doi.org/10.3390/pharmaceutics14071512