miR‐122 and the WNT/β‐catenin pathway inhibit effects of both interleukin‐1β and tumor necrosis factor‐α in articular chondrocytes in vitro

Interleukin‐1β (IL‐1β), tumor necrosis factor‐α (TNF‐α), and WNT/β‐catenin signaling cause dysregulation of rat primary articular chondrocytes (rArCs), resulting in cartilage extracellular matrix destruction and osteoarthritis (OA) progression. microRNA (miR) miR‐122 represses these effects whereas...

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Detalles Bibliográficos
Autores principales: Scott, Kayla M., Cohen, D. Joshua, Boyan, Barbara D., Schwartz, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320820/
https://www.ncbi.nlm.nih.gov/pubmed/35362116
http://dx.doi.org/10.1002/jcb.30244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320820/
https://www.ncbi.nlm.nih.gov/pubmed/35362116
http://dx.doi.org/10.1002/jcb.30244

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