miR‐122 and the WNT/β‐catenin pathway inhibit effects of both interleukin‐1β and tumor necrosis factor‐α in articular chondrocytes in vitro

Interleukin‐1β (IL‐1β), tumor necrosis factor‐α (TNF‐α), and WNT/β‐catenin signaling cause dysregulation of rat primary articular chondrocytes (rArCs), resulting in cartilage extracellular matrix destruction and osteoarthritis (OA) progression. microRNA (miR) miR‐122 represses these effects whereas...

Descripción completa

Detalles Bibliográficos
Autores principales: Scott, Kayla M., Cohen, D. Joshua, Boyan, Barbara D., Schwartz, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320820/
https://www.ncbi.nlm.nih.gov/pubmed/35362116
http://dx.doi.org/10.1002/jcb.30244

Ejemplares similares

Ejemplares similares