Inhibition of Microtubule Affinity Regulating Kinase 4 by Metformin: Exploring the Neuroprotective Potential of Antidiabetic Drug through Spectroscopic and Computational Approaches

Microtubule affinity regulating kinase 4 (MARK4) regulates the mechanism of microtubules by its ability to phosphorylate the microtubule-associated proteins (MAP’s). MARK4 is known for its major role in tau phosphorylation via phosphorylating Ser(262) residue in the KXGS motif, which results in the...

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Detalles Bibliográficos
Autores principales: Ashraf, Ghulam Md., DasGupta, Debarati, Alam, Mohammad Zubair, Baeesa, Saleh S., Alghamdi, Badrah S., Anwar, Firoz, Alqurashi, Thamer M. A., Sharaf, Sharaf E., Al Abdulmonem, Waleed, Alyousef, Mohammed A., Alhumaydhi, Fahad A., Shamsi, Anas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320910/
https://www.ncbi.nlm.nih.gov/pubmed/35889524
http://dx.doi.org/10.3390/molecules27144652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320910/
https://www.ncbi.nlm.nih.gov/pubmed/35889524
http://dx.doi.org/10.3390/molecules27144652

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