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Rational Guidelines for the Two‐Step Scalability of Enzymatic Polycondensation: Experimental and Computational Optimization of the Enzymatic Synthesis of Poly(glycerolazelate)

The lipase‐catalyzed polycondensation of azelaic acid and glycerol is investigated according to a Design‐of‐Experiment approach that helps to elucidate the effect of experimental variables on monomer conversion, M (n) and regioselectivity of acylation of glycerol. Chemometric analysis shows that aft...

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Detalles Bibliográficos
Autores principales: Todea, Anamaria, Fortuna, Sara, Ebert, Cynthia, Asaro, Fioretta, Tomada, Stefano, Cespugli, Marco, Hollan, Fabio, Gardossi, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320960/
https://www.ncbi.nlm.nih.gov/pubmed/35199480
http://dx.doi.org/10.1002/cssc.202102657