Antibodies to Cartilage Oligomeric Matrix Protein Are Pathogenic in Mice and May Be Clinically Relevant in Rheumatoid Arthritis

OBJECTIVE: Cartilage oligomeric matrix protein (COMP) is an autoantigen in rheumatoid arthritis (RA) and experimental models of arthritis. This study was undertaken to investigate the structure, function, and relevance of anti‐COMP antibodies. METHODS: We investigated the pathogenicity of monoclonal...

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Detalles Bibliográficos
Autores principales: Ge, Changrong, Tong, Dongmei, Lönnblom, Erik, Liang, Bibo, Cai, Weiwei, Fahlquist‐Hagert, Cecilia, Li, Taotao, Kastbom, Alf, Gjertsson, Inger, Dobritzsch, Doreen, Holmdahl, Rikard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2022
Materias:
Rheumatoid Arthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320966/
https://www.ncbi.nlm.nih.gov/pubmed/35080151
http://dx.doi.org/10.1002/art.42072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320966/
https://www.ncbi.nlm.nih.gov/pubmed/35080151
http://dx.doi.org/10.1002/art.42072

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