Nanoporous Gold Catalyst for the Oxidative N‐Dealkylation of Drug Molecules: A Method for Synthesis of N‐Dealkylated Metabolites

A novel method for the selective catalytic N‐dealkylation of drug molecules on a nanoporous gold (NPG) catalyst producing valuable N‐dealkylated metabolites and intermediates is described. Drug metabolites are important chemical entities at every stage of drug discovery and development, from explora...

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Detalles Bibliográficos
Autores principales: Alipour Najmi, Ali, Jafariyeh‐Yazdi, Elchin, Hadian, Mojgan, Hermans, Jos, Bischoff, Rainer, Yue, Jun, Dömling, Alexander, Wittstock, Arne, Permentier, Hjalmar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320976/
https://www.ncbi.nlm.nih.gov/pubmed/35303400
http://dx.doi.org/10.1002/cmdc.202200040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320976/
https://www.ncbi.nlm.nih.gov/pubmed/35303400
http://dx.doi.org/10.1002/cmdc.202200040

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