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Cell Subsampling Recovers Probative DNA Profile Information from Unresolvable/Undetectable Minor Donors in Mixtures

When a minor DNA component to a binary mixture is present at a weight ratio of approximately 1:50 or less, the presence of this minor donor is undetectable (or barely detectable) by standard mixture deconvolution approaches. In an attempt to retrieve probative minor donor DNA profile information, mu...

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Detalles Bibliográficos
Autores principales: Huffman, Kaitlin, Hanson, Erin, Ballantyne, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321018/
https://www.ncbi.nlm.nih.gov/pubmed/35885899
http://dx.doi.org/10.3390/genes13071117