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Efficient Induction of Antigen-Specific CD8(+) T-Cell Responses by Cationic Peptide-Based mRNA Nanoparticles

A major determinant for the success of mRNA-based vaccines is the composition of the nanoparticles (NPs) used for formulation and delivery. Cationic peptides represent interesting candidate carriers for mRNA, since they have been shown to efficiently deliver nucleic acids to eukaryotic cells. mRNA N...

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Detalles Bibliográficos
Autores principales: D’haese, Sigrid, Laeremans, Thessa, den Roover, Sabine, Allard, Sabine D., Vanham, Guido, Aerts, Joeri L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321026/
https://www.ncbi.nlm.nih.gov/pubmed/35890284
http://dx.doi.org/10.3390/pharmaceutics14071387