Hirsutanone Isolated from the Bark of Alnus japonica Attenuates Melanogenesis via Dual Inhibition of Tyrosinase Activity and Expression of Melanogenic Proteins

Hirsutanone (Hir) and oregonin (Ore) are diarylheptanoids isolated from the bark of Alnus japonica. In this study, we investigated the anti-melanogenic activity of Hir and Ore in B16-F1 murine melanoma and normal human epidermal melanocytes (HEMn-DP) and elucidated the mechanisms of action. In B16-F...

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Detalles Bibliográficos
Autores principales: Uto, Takuhiro, Tung, Nguyen Huu, Shoyama, Yukihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321039/
https://www.ncbi.nlm.nih.gov/pubmed/35890509
http://dx.doi.org/10.3390/plants11141875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321039/
https://www.ncbi.nlm.nih.gov/pubmed/35890509
http://dx.doi.org/10.3390/plants11141875

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