Hemagglutinin Subtype Specificity and Mechanisms of Highly Pathogenic Avian Influenza Virus Genesis

Highly Pathogenic Avian Influenza Viruses (HPAIVs) arise from low pathogenic precursors following spillover from wild waterfowl into poultry populations. The main virulence determinant of HPAIVs is the presence of a multi-basic cleavage site (MBCS) in the hemagglutinin (HA) glycoprotein. The MBCS al...

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Detalles Bibliográficos
Autores principales: de Bruin, Anja C. M., Funk, Mathis, Spronken, Monique I., Gultyaev, Alexander P., Fouchier, Ron A. M., Richard, Mathilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321182/
https://www.ncbi.nlm.nih.gov/pubmed/35891546
http://dx.doi.org/10.3390/v14071566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321182/
https://www.ncbi.nlm.nih.gov/pubmed/35891546
http://dx.doi.org/10.3390/v14071566

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