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Hemagglutinin Subtype Specificity and Mechanisms of Highly Pathogenic Avian Influenza Virus Genesis
Highly Pathogenic Avian Influenza Viruses (HPAIVs) arise from low pathogenic precursors following spillover from wild waterfowl into poultry populations. The main virulence determinant of HPAIVs is the presence of a multi-basic cleavage site (MBCS) in the hemagglutinin (HA) glycoprotein. The MBCS al...
Autores principales: | de Bruin, Anja C. M., Funk, Mathis, Spronken, Monique I., Gultyaev, Alexander P., Fouchier, Ron A. M., Richard, Mathilde |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321182/ https://www.ncbi.nlm.nih.gov/pubmed/35891546 http://dx.doi.org/10.3390/v14071566 |
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