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Assessing the Immunomodulatory Effect of Size on the Uptake and Immunogenicity of Influenza- and Hepatitis B Subunit Vaccines In Vitro

Viral subunit vaccines are a safer and more tolerable alternative to whole inactivated virus vaccines. However, they often come with limited efficacy, necessitating the use of adjuvants. Using free and particle-bound viral antigens, we assessed whether size affects the uptake of those antigens by hu...

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Detalles Bibliográficos
Autores principales: Heida, Rick, Born, Philip A., Tapia-Calle, Gabriela, Frijlink, Henderik W., Salvati, Anna, Huckriede, Anke L. W., Hinrichs, Wouter L. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321264/
https://www.ncbi.nlm.nih.gov/pubmed/35890185
http://dx.doi.org/10.3390/ph15070887