Preparation and Evaluation of Mucus-Penetrating Inhalable Microparticles of Tiotropium Bromide Containing Sodium Glycocholate

This study aimed to prepare mucus-penetrating inhalable microparticles for dry powder inhalers and to evaluate their applicability in an asthma-induced rat model. Microparticles were prepared from water solutions containing tiotropium bromide, L-leucine, and sodium glycocholate (NaGc) as permeation...

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Detalles Bibliográficos
Autores principales: Kwon, Yong-Bin, Kang, Ji-Hyun, Kim, Young-Jin, Kim, Dong-Wook, Lee, Sung-Hoon, Park, Chun-Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321333/
https://www.ncbi.nlm.nih.gov/pubmed/35890304
http://dx.doi.org/10.3390/pharmaceutics14071409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321333/
https://www.ncbi.nlm.nih.gov/pubmed/35890304
http://dx.doi.org/10.3390/pharmaceutics14071409

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