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Preparation and Evaluation of Mucus-Penetrating Inhalable Microparticles of Tiotropium Bromide Containing Sodium Glycocholate
This study aimed to prepare mucus-penetrating inhalable microparticles for dry powder inhalers and to evaluate their applicability in an asthma-induced rat model. Microparticles were prepared from water solutions containing tiotropium bromide, L-leucine, and sodium glycocholate (NaGc) as permeation...
Autores principales: | Kwon, Yong-Bin, Kang, Ji-Hyun, Kim, Young-Jin, Kim, Dong-Wook, Lee, Sung-Hoon, Park, Chun-Woong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321333/ https://www.ncbi.nlm.nih.gov/pubmed/35890304 http://dx.doi.org/10.3390/pharmaceutics14071409 |
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